Injectable collagen stimulation injections have been available since early 2000s.  

The information on this page for Bio-Collagen Stimulators will assist your understanding of these products during your consultation with our doctor. 

Due to TGA regulations, we cannot put before and after photos or use the trade names of bio-stimulators on this webpage.  

Dr Janet offers a few choices of Bio-stimulators from well established collagen stimulating products from USA to those recently approved by TGA in 2024/25 from Korea, which can be used both for volume correction, as well as improving skin texture, improve skin thickness and density and overall improving skin quality.

Both our doctors have many years experience with Bio-regenerative Collagen Bio-stimulators. 

What is the difference between Bio-stimulators and Traditional Temporary Gel Facial Fillers?

Temporary gel fillers are water binding materials that occupy space in the tissues and they give instant results.  These gels breakdown over 6-12 months, but may last longer than initially thought. Complications may include nodules, foreign body reactions, residual product migration and over-filling.

Generally these temporary gels have minimal collagen stimulation capacity.

True collagen stimulators and true bio-regenerative type products, have greater bio-stimulatory effect, and most patients will notice an improvement in the quality of their skin but results may vary between individuals and therefore a thorough assessment and consultation is essential prior to treatments to discuss realistic expectations, possible complications, treatment planning and costs. 

For patients who have lost a lot of volume in their face and require a lot of temporary gel fillers, or patients who “burn” through their temporary gel fillers quickly,  bio-stimulators may be a more cost effective alternative option.  

What happens to our skin after menopause?

After mid 20s, we lose about 1% of collagen per year from our face, causing our skin to be thinner as we age.  After menopause we lose even more collagen, up to 30% in the first 5 years of menopause, both in our skin and our bones.  Hence patients do ask our doctors to discuss treatments that may address these concerns.  

The aesthestic management of menopausal women is different to treating a women who are younger.  

You will need a thorough consultation, treatment planning and informed consent prior to collagen Biostimulator treatments. 

Injectable Bio-stimulators are prescription only medicines in Australia and a personalised doctor’s consultation is essential.  

Main advantages and benefits of Biostimulators:  

Improvements in volume occur gradually over a few months. 

Generally a few treatments may be required. 

Once your skin forms its own collagen, it takes longer for this collagen to breakdown.

Hence, results may last 12-24 months, longer than the average temporary gel products.  

As collagen remodelling and collagen contraction occur overtime, most patients will also notice  “firmness” in the skin.

Areas that can be treated include: temporal hollowness, firming lateral high cheek, lateral jawline including pre-auricular region, jowls, neck and decolletage as well as hands. 

Disadvantages: 

Higher upfront cost (when compared to traditional cosmetic injections) and for some biostimulators, a few treatments are required. 

Results are not immediate, as collagen production takes time, the improvements may take a few weeks to 1-2 months to become visible. 

Most Collagen Biostimulators are not suitable for lips and the thin skin around the eyes (periorbital) region as there is a small risk of nodules.  Only one TGA approved Korean Bio-stimulation product is approved for treatment near the eyes.  

Some patients with active autoimmune disorders may not be suitable for bio-stimulator injections.  A full medical history is essential to exclude contra-indications.

If you are considering a surgical facelift, you may wish to avoid collagen stimulators for 1-2 years before the surgery, to reduce the collagen fibres under the skin during the surgery.  

Other treatment risks are similar to traditional cosmetic injections includes pain, bruising, swelling, foreign body reaction, lumpiness, vascular occlusion and blindness.